This could be the exact moment when the "McCain-Palin 2008" campaign "ended." At least in terms of "performance." McCain entirely "lost himself" here. The goal for any "candidate" in a nationally televised "debate" isn't to fire up "the base" -- the mission is to "convince" the last remaining "undecided voters" (who are ridiculous, but important).
And McCain, all full of piss and vinegar, slipped into a place in which we was talking to the party base -- the radical anti-choice Christian far-right. It was a colossal blunder for McCain. It was something a "green-behind-the-ears" rookie running for Congress would do. Not a major party presidential nominee.
It was another McCain "that one" moment, only this time, he offended undecided voters, women, mothers, moderate pro-choice Republicans... everyone except the far-right base. This is why he's not ready to be president. He simply doesn't have the self control for the job.